Congo Mystery Illness: Symptoms Revealed as Deaths Surge Before Age 50

Congo Mystery Illness: Symptoms Revealed as Deaths Surge Before Age 50

Mystery Illness Claims Lives in Congo, WHO Investigates

A concerning outbreak of an unknown illness in northwestern Congo has resulted in over 50 deaths within a mere five weeks, according to the World Health Association (WHO). As the initial discovery on Jan. 21, more than 400 cases have been reported.

Rapid Progression of Symptoms

Medical professionals on the ground are notably alarmed by the rapid progression of the illness. Symptoms, including fever, vomiting, and internal bleeding, lead to death in approximately 48 hours. “That’s what’s really worrying,” saeid Serge Ngalebato, medical director of bikoro Hospital, a regional monitoring center.

Ruling Out Known Pathogens

The symptoms, characterized as “hemorrhagic fever,” initially prompted concerns about familiar deadly viruses like Ebola, dengue, Marburg, and yellow fever.Though, laboratory tests on more than a dozen samples have ruled out these possibilities.

Possible Zoonotic transmission

The outbreak’s origin is traced back to the town of Boloko,where three children died after consuming a bat. This incident underscores the ongoing concerns about zoonotic diseases – illnesses that jump from animals to humans – particularly in regions where wild animal consumption is prevalent.

Surge in Outbreaks

The WHO reported in 2022 that Africa has seen a surge of more than 60% in such outbreaks over the past decade,raising concerns about the continent’s vulnerability to emerging infectious diseases.

Malaria as a Potential Factor

Following a second outbreak in Bomate village on Feb. 9, further testing was conducted. While common hemorrhagic fever diseases were ruled out, some samples tested positive for malaria. Last year, a similar mystery illness with flu-like symptoms that caused dozens of deaths in Congo was later attributed to malaria. This raises the possibility that malaria or a co-infection could be playing a role in the current outbreak.

WHO response and Ongoing Challenges

The WHO is actively involved, providing medical supplies, supporting local health workers, and coordinating the emergency response. However, the surge in violence in eastern Congo has complicated matters, leading to the destruction of vital health infrastructure and exacerbating an “already dire situation” for millions.

Congo’s Battle with Mpox

adding to the healthcare challenges, Congo is currently grappling with a significant Mpox epidemic. Official data indicates 79,519 suspected cases and 1,507 deaths across the country’s 26 provinces between early 2024 and mid-February 2025. In response, the Ministry of Public Health, Hygiene and Social Welfare recently launched a Mpox vaccination campaign targeting over 660,000 people.

Looking Ahead: Strengthening Disease Surveillance

The ongoing investigation into this unknown illness highlights the critical need for robust disease surveillance systems, particularly in regions prone to zoonotic diseases. Strengthening these systems, along with improving healthcare infrastructure and addressing underlying issues such as food security and conflict, is essential to prevent future outbreaks and protect vulnerable populations. As the WHO continues its investigation, ongoing vigilance and proactive measures are paramount to containing the spread of this deadly illness and safeguarding public health.

How prevalent are zoonotic diseases in Congo, and what steps can be taken to mitigate their spread?

Exclusive Interview with Dr. Amina Kibangula on the Congo Mystery Illness Outbreak

Archyde’s correspondent recently caught up with Dr. Amina Kibangula, an eminent epidemiologist and advisor to the Congolese Ministry of Public Health, to discuss the ongoing mystery illness outbreak in northwestern Congo. Dr. Kibangula shares her insights into this perplexing health crisis and the international response.

Rapid Spread and Symptoms

Archyde: Dr. Kibangula, this outbreak is progressing rapidly. More then 400 cases and over 50 deaths in just five weeks. What are the primary symptoms,and why is it so alarming?

Dr. Kibangula: Indeed, the speed at which this illness is progressing is deeply concerning. The primary symptoms include fever,vomiting,and internal bleeding. The mortality rate is high, with deaths occurring within approximately 48 hours of the first symptoms. This rapid progression is what’s really worrying health professionals.”

Ruling Out Known Pathogens

Archyde: Initial concerns circled around familiar viruses like Ebola. What have laboratory results shown so far?

dr. Kibangula: Laboratory tests on over a dozen samples have ruled out known pathogens such as Ebola, dengue, Marburg, and yellow fever.This Mystery illness, therefore, seems to be an unfamiliar agent, making it even more challenging to contain and treat.

Possible Zoonotic Transmission

Archyde: The outbreak’s origin appears to be linked to consuming a bat in Boloko. How prevalent are zoonotic diseases in Congo, and what can be done to mitigate their spread?

Dr. Kibangula: Zoonotic diseases,illnesses that jump from animals to humans,are indeed a concern in Congo,especially in rural areas where wild animal consumption is common. Strengthening surveillance systems, promoting food safety education, and improving healthcare infrastructure can significantly help mitigate their spread.

Malaria as a Potential Factor

Archyde: Some samples tested positive for malaria. How might malaria or a co-infection be contributing to this outbreak?

Dr. Kibangula: While we can’t conclude just yet, it’s possible that malaria or a co-infection could be playing a role in this outbreak.Last year, a similar mystery illness was later attributed to malaria. We’re considering all possibilities as we continue our examination.

International Response and Challenges

Archyde: The WHO is actively involved. How can the international community further assist in containing this outbreak?

Dr. Kibangula: We appreciate the WHO’s support and the international community’s concern. strengthening our disease surveillance systems, improving healthcare infrastructure, and addressing underlying issues like conflict and food security are critical in managing this outbreak and preventing future ones.

Thoughts on the Future of Global health

Archyde: given the surge in outbreaks across Africa over the past decade, what steps should the global health community take to better prepare and respond to emerging infectious diseases?

Dr. Kibangula: We need robust and sustained investment in public health, focusing on prevention, detection, and response. Enhancing global cooperation,improving data sharing,and supporting local health systems will be key to staying ahead of emerging threats. We must also consider the impact of climate change and human-wildlife interaction on disease transmission. It’s a complex issue requiring a multi-faceted approach.”

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